猫传染性腹膜炎（FIP）：从"绝症"到可治疗，识别与用药认知更新

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   Feline Infectious Peritonitis: European Advisory Board on Cat Diseases Guidelines

   Tasker S, Addie DD, Egberink H, Hofmann-Lehmann R 等 · Viruses · 2023

   👉 ABCD 指南：FIP 的免疫介导机制、综合诊断路径与管理原则。

   PubMed 原文 ↗Europe PMC 镜像 ↗DOI 全文 ↗按标题检索 ↗DOI 10.3390/v15091847

   展开原文摘要（英文，1346 字）

   Feline coronavirus (FCoV) is a ubiquitous RNA virus of cats, which is transmitted faeco-orally. In these guidelines, the European Advisory Board on Cat Diseases (ABCD) presents a comprehensive review of feline infectious peritonitis (FIP). FCoV is primarily an enteric virus and most infections do not cause clinical signs, or result in only enteritis, but a small proportion of FCoV-infected cats develop FIP. The pathology in FIP comprises a perivascular phlebitis that can affect any organ. Cats under two years old are most frequently affected by FIP. Most cats present with fever, anorexia, and weight loss; many have effusions, and some have ocular and/or neurological signs. Making a diagnosis is complex and ABCD FIP Diagnostic Approach Tools are available to aid veterinarians. Sampling an effusion, when present, for cytology, biochemistry, and FCoV RNA or FCoV antigen detection is very useful diagnostically. In the absence of an effusion, fine-needle aspirates from affected organs for cytology and FCoV RNA or FCoV antigen detection are helpful. Definitive diagnosis usually requires histopathology with FCoV antigen detection. Antiviral treatments now enable recovery in many cases from this previously fatal disease; nucleoside analogues (e.g., oral GS-441524) are very effective, although they are not available in all countries.